An outstretched, upturned hand with a spiral galaxy emerging above it reads as a statement about creation, reach, or the idea of holding something vast within human scale. It draws loosely on creation myth imagery (a hand giving rise to the cosmos) without tying to one specific tradition, so people read into it what they want: spirituality, ambition, curiosity about the universe, or simply the contrast between the small and the infinite. Because the symbolism is open-ended rather than fixed to a single belief system, it tends to appeal broadly rather than carrying one settled meaning.
Where it sits
The vertical stacking of hand below and galaxy above suits the forearm, upper arm, or spine, where the elongated shape can run naturally with the limb or body line. It could also work across the ribs or thigh if rotated slightly to follow the body's contour. Shrinking it down would blur the fine stippling in the galaxy's dust clouds and the palm's linework, so it needs a reasonably long, unbroken stretch of skin to hold both halves clearly.
Making it yours
Ask an artist for any of these.